This course will introduce students to the fundamentals of photophysics, photochemistry, and photobiology. Engineering of selective photosensitizers, optically active nanomedicine and alternative light sources for photodynamic therapy, photothermal therapy, and imaging will be covered. Other light-based therapies, including laser surgery, low-level light therapy, and light-activated tissue repair and regeneration, will also be featured. The course will briefly cover radiation, magnetic, and ultrasound-based technologies to highlight other extrinsic activation mechanisms for drug delivery and phototherapy. Students will have the opportunity to review and present research articles on these emerging phototherapies and participate in lab experiments to gain a greater awareness of current advancements and refine skills in literature review.