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Courses - Spring 2023
BCHM
Biochemistry Department Site
The College of Computer, Mathematical and Natural Sciences enforces course prerequisites. Students who do not meet the course prerequisites will be administratively dropped from the course.

Registration in course sections which begin with "SES*" is restricted to students admitted into the Science in the Evening Program, administered through the Office of Extended Studies. For complete information, visit: http://oes.umd.edu/index.php?slab=sie , e-mail oes@umd.edu, or call 301-405-7762.

BCHM461
Credits: 3
Grad Meth: Reg, P-F, Aud
Prerequisite: Minimum grade of C- in CHEM271 and CHEM272; or minimum grade of C- in CHEM276 and CHEM277.
Credit only granted for: BCHM461 or BCHM463.
First semester of a comprehensive introduction to modern biochemistry. Structure, chemical properties, and function of proteins and enzymes, carbohydrates, lipids, and nucleic acids. Basic enzyme kinetics and catalytic mechanisms.
BCHM462
Credits: 3
Grad Meth: Reg, P-F, Aud
Prerequisite: Minimum grade of C- in BCHM461.
Credit only granted for: BCHM462 or BCHM463.
A continuation of BCHM 461. Metabolic pathways and metabolic regulation, energy transduction in biological systems, enzyme catalytic mechanisms.
BCHM463
Biochemistry of Physiology
Credits: 3
Grad Meth: Reg, P-F, Aud
Prerequisite: Minimum grade of C- in CHEM271 and CHEM272; or minimum grade of C- in CHEM276 and CHEM277.
Credit only granted for: BCHM461, BCHM462 or BCHM463.
A one-semester introduction to general biochemistry. A study of protein structure, enzyme catalysis, metabolism, and metabolic regulation with respect to their relationship to physiology.
BCHM464
Biochemistry Laboratory
Credits: 3
Grad Meth: Reg, P-F, Aud
Prerequisite: BCHM461 or BCHM463; and a grade of C- or better in the prerequisite is required for all College of Computer, Mathematical, and Natural Sciences majors and recommended for all students.
Corequisite: BCHM465.
Restriction: BCHM, CHEM, and Nutritional Sciences majors have first priority, followed by other life science majors.
Biochemical and genetic methods for studying protein function. Site-directed mutagenesis and molecular cloning, protein purification, enzyme activity assays, computer modeling of protein structure.
Students must pay a $40.00 lab materials fee.
BCHM465
Credits: 3
Grad Meth: Reg, P-F, Aud
Prerequisite: BCHM461 or BCHM463; and a grade of C- or better in the prerequisite is required for College of Computer, Mathematical, and Natural Sciences majors and recommended for all students.
Recommended: BCHM462.
CORE Capstone (CS) Course. An advanced course in biochemistry. Biochemical approach to cellular information processing. DNA and RNA structure. DNA replication, transcription, and repair. Translation of mRNA to make proteins.
BCHM485
Physical Biochemistry
Credits: 3
Grad Meth: Reg, P-F, Aud
Prerequisite: Minimum grade of C- in CHEM481.
Restriction: Must be in Biochemistry program; or permission of instructor.
Credit only granted for: CHEM482 or BCHM485.
Physical Chemistry with applications to biological systems. Principal topics: quantum chemistry, spectroscopy, structural methods for biological macromolecules, statistical thermodynamics, transport processes in liquid phase, chemical and biochemical kinetics, modeling and simulation, polymer dynamics.
BCHM669C
Special Topics in Biochemistry; Protein Folding and Disease
Credits: 3
Grad Meth: Reg, Aud
BCHM 669C applies the principles of protein biochemistry towards an understanding of the molecular basis for a range of human diseases. Therapeutic approaches, including small molecules, protein design, and immunotherapy will be discussed.
BCHM669D
Special Topics in Biochemistry; Drug Discovery
Credits: 3
Grad Meth: Reg, Aud
Overview of the drug discovery process covering the identification of drug targets, assay development, high throughput compound screening, mechanism-based drug design, compound optimization, computational methods, pharmacokinetic/toxicity studies, vaccine and biologics, phage-based drug discovery, drug delivery.
BCHM675
Biophysical Chemistry
Credits: 3
Grad Meth: Reg, Aud
Prerequisite: CHEM481 and BCHM461; or students who have taken courses with comparable content may contact the department.
Conformation, shape, structure, conformational changes, dynamics and interactions of biological macromolecules and complexes or arrays of macromolecules. Physical techniques for studying properties of biological macromolecules.
BCHM676
Biological Mass Spectrometry
Credits: 3
Grad Meth: Reg, Aud
Prerequisite: BCHM461 or BCHM463.
Formerly: BCHM669B.
Fundamentals of modern mass spectrometry and use with biochemical techniques to provide unique analyses of drug metabolites, lipids, carbohydrates, nucleotides and proteins. The interface with bioinformatics will be examined, which provides the foundation of proteomics.
BCHM698
(Perm Req)
Literature Seminar in Biochemistry
Credits: 2
Grad Meth: Reg
BCHM699
Special Problems in Biochemistry
Credits: 1 - 6
Grad Meth: Reg, Aud
Open only to non-thesis M.S. degree candidates.
Contact department for information to register for this course.
BCHM799
Master's Thesis Research
Credits: 1 - 6
Grad Meth: S-F
Contact department for information to register for this course.
BCHM889A
BCHM889B
(Perm Req)
BCHM889D
(Perm Req)
Seminar; Enzymology of Recombination
Credits: 1
Grad Meth: Reg, Aud
BCHM889G
(Perm Req)
Seminar; Biological Mass Spectrometry
Credits: 1
Grad Meth: Reg, Aud
BCHM889M
Seminar; Modern Methods in NMR and Structural Biology
Credits: 1
Grad Meth: Reg, Aud
BCHM898
Pre-Candidacy Research
Credits: 1 - 8
Grad Meth: Reg
Contact department for information to register for this course.
BCHM899
(Perm Req)
Doctoral Dissertation Research
Credits: 6
Grad Meth: S-F
Contact department for information to register for this course.