The fundamentals of nanomanufacturing based on state-of-the-art and future prospects in materials design and systems integration. The course examines functional nanomaterials design and synthesis, structural assembly from nanoscale to macroscale, and device fabrication. Distinct from the current curricular paradigm in many nanotechnology programs that focus on underlying science, this course emphasizes the immediate need for scale-up, process robustness, and system integration issues. Featuring case studies from industry, end of chapter problems, and study questions, the course is for upper-level undergraduate and graduate students, who are interested in the future of manufacturing innovation and technology.