Courses - Spring 2023
BIOE120
Biology for Engineers
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: Must have completed or be concurrently enrolled in MATH140.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Introduction to the functions and interactions of biological systems from a quantitative perspective. Introduction to the modern experimental techniques and methods of data analysis. Roles for bioengineers in biology, and the role of biology in bioengineering will be elucidated.
BIOE121
Biology for Engineers Laboratory
Credits:
1
Grad Meth:
Reg, P-F, Aud
Prerequisite: Must have completed or be concurrently enrolled in BIOE120.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Bioengineering encompasses numerous sub-disciplines that apply engineering principles to analyze biological systems and that utilize engineering design strategies to solve biological and biomedical problems. This course is aimed at providing students with the opportunity to learn how biology and engineering can synergistically contribute to our understanding of such problems, and to gain hands-on experience in basic techniques relevant to Bioengineering.
BIOE221
Academic and Career Planning
Credits:
1
Grad Meth:
Reg, P-F
Prerequisite: BIOE120 and BIOE121.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Provides practical tools to help Bioengineering majors think critically about their goals and career paths. Guides Bioengineering students through accessing useful resources both on- and off-campus.
BIOE232
Bioengineering Thermodynamics
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: PHYS261 and PHYS260.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE232, ENES232, ENME232, or ENME320.
A quantitative introduction to thermodynamic analysis of bioengineering systems. Bioengineering encompasses a wide range of applications from nanoscale interactions (e.g. reactions between molecules), to cellular interactions (e.g. membrane electrical currents), to overall balances on organisms, all the way to large scale manufacturing. Each of these applications (and many others not mentioned) involve energy interactions which is the domain of thermodynamics. The basic laws of thermodynamics will be introduced and explained through a series of examples related to bioengineering systems.
BIOE241
Biocomputational Methods
Credits:
3
Grad Meth:
Reg, P-F, Aud
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Application of computer technology to biological and natural resource systems considering engineering aspects. Designed to help students in the use of computer technology for problem solving. The course will cover 4-5 software packages important for later use by the student.
BIOE331
Biofluids
Credits:
3
Grad Meth:
Reg, P-F
Prerequisite: MATH246, BIOE120, BIOE121, BIOE241, and BIOE371; and must have completed or be concurrently enrolled in BIOE232.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE331, ENCE305, ENFP300 or ENME331.
Principles and applications of fluid mechanics with a focus on bioengineering topics. Content includes conservation of mass, momentum, and energy, as well as the application of these fundamental relations to hydrostatics, control volume analysis, internal and external flow, and boundary layers. Applications to biological and bioengineering problems such as tissue engineering, bioprocessing, imaging, and drug delivery.
BIOE340
Modeling Physiological Systems and Lab
Credits:
4
Grad Meth:
Reg, P-F, Aud
Prerequisite: BSCI330, BIOE120, BIOE121, BIOE241, and MATH246.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE340 or (BSCI440 and BSCI441).
Topics covered will include cell and general physiology, membrane physiology, blood cells and clotting, circulation, metabolism, respiration, and the nervous system. A lab component will also be included.
BIOE371
Linear Systems and Ordinary Differential Equations for Bioengineering Applications
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE241; and must have completed or be concurrently enrolled in MATH246.
Restriction: Permission on ENGR-Fischell Department of Bioengineering department.
This class utilizes fundamentals in linear systems, including eigenvalues and eigenvectors, as well as linear differential equations, to study various problems in bioengineering and biological systems, with a particular emphasis on feedback, stability, controllability, and control design.
BIOE372
Biostatistics for Experimental Design and Data Analysis
Credits:
3
Grad Meth:
Reg, P-F
Prerequisite: BIOE120, BIOE121, and BIOE241.
Recommended: MATH246.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE372 or STAT464.
This course will instruct students in the fundamentals of probability and statistics through examples in biological phenomenon, the design of bioengineering experiments, and clinical data analysis. Fundamentals covered in the course include probability distributions, hypothesis testing, power analysis, regression analysis, and correlation analysis.
BIOE386
Bioengineering Design and Teamwork
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120, BIOE121, BIOE241, MATH246.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department and must have earned a minimum of 60 credits.
Focuses on the engineering design process, including needs finding, problem definition, inclusive design, and prototyping. Students will join an existing senior capstone design team and contribute to the project. This elective is designed to be taken directly prior to BIOE485, and will collaborate with the students and projects in that course. Students who complete BIOE386 may have the option to continue their capstone project in BIOE485.
BIOE389C
Special Projects in Bioengineering; Bioengineering Design Competitions
Credits:
1
Grad Meth:
Reg, P-F
BIOE389 cannot be used as a technical elective towards the BIOE curriculum requirements.
BIOE389F
Special Projects in Bioengineering; iGEM Research Seminar
Credits:
2
Grad Meth:
Reg, P-F, Aud
Cross-listed with BSCI338F. Credit granted for BSCI338F or BIOE389F.
BIOE399
Independent Study in Bioengineering
Credits:
1 - 3
Grad Meth:
Reg, P-F, Aud
Prerequisite: permission of department.
BIOE399H
Independent Study in Bioengineering
Credits:
1 - 3
Grad Meth:
Reg, P-F, Aud
BIOE404
Biomechanics
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: MATH246, BIOE120, ENES102, BIOE121, and BIOE241; and must have completed or be concurrently enrolled in BIOE371.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Introduction to the fundamentals of biomechanics including force analysis, mechanics of deformable bodies, stress and strain, multiaxial deformations, stress analysis, and viscoelasticity. Biomechanics of soft and hard tissues.
BIOE411
Tissue Engineering
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: Must have completed at least one biology course; and (BIOE120, BIOE121, BIOE241, MATH246, and MATH241). Or permission of ENGR-Fischell Department of Bioengineering department.
Recommended: BSCI330 and BIOE340.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE411 or CHBE487.
A review of the fundamental principles involved in the design of engineered tissues and organs. Both biological and engineering fundamentals will be considered.
BIOE414
Macroscale Biomechanics
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120, BIOE121, BIOE241, MATH246, and ENES102.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE414 or BIOE489Z.
Formerly: BIOE489Z.
An overview of current problems in movement biomechanics. After taking this course, students will be able to 1) Describe the engineering tools needed to study human movement 2) Recognize a variety of clinical research and practice, and 3) Use the framework provided by the course to pursue their own self-teaching and research on these topics. Topics covered include muscle mechanics, joint mechanics, EMG and EEG signal applications, ultrasonography and elastography, anthropometry, human movement 3-D kinematics, inverse dynamics, forward dynamics, work, power and energy. Biomechanics tools will be used to investigate clinical problems. Students will also do research projects on related topics.
BIOE433
Optical Microscopy
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120, BIOE121, BIOE241, BIOE371, and MATH246.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE489I or BIOE433.
Formerly: BIOE489I.
Includes a large variety of techniques central in many fields of biological and engineering research as well as clinical medicine. This course will provide a comprehensive overview of the fundamentals of optical microscopy. At a fundamental level, the course will cover the interaction of light with tissue, cells and biomaterials, and the mathematical foundations that describe optical systems.
BIOE442
Python: Introduction to Programming and Data Analysis
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE241, BIOE120, BIOE121, and MATH241; or permission of ENGR-Fischell Department of Bioengineering department.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE489A or BIOE442.
Formerly: BIOE489A.
Provides an introduction to structured programming, computational methods, and data analysis techniques with the goal of building a foundation allowing students to confidently address problems in research and industry. Fundamentals of programming, algorithms, and simulation are covered from a general computer science perspective, while the applied data analysis and visualization portion makes use of the Python SciPy stack.
BIOE447
Clinical Experiences in Bioengineering
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE221.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE489O or BIOE447.
Formerly: BIOE489O.
An immersion experience in the clinical settings in which biomedical engineering strategies, technologies, and practices are applied. An emphasis will be placed on both clinical problems and engineering solutions.
BIOE453
Biomaterials
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: CHEM231, MATH246, CHEM232, BIOE120, BIOE121, and BIOE241.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE453, CHBE457, or ENMA425.
Examination of the structure and function of natural biomaterials, and cell-extracellular matrix interactions. Study physical properties of synthetic biomaterials for biomedical applications. Understanding molecular level interactions between biomolecules and biomaterials to design novel biomaterials with desirable characteristics. Application of biomaterials as implants, drug delivery systems, biosensors, engineered materials such as artificial skin and bone growth scaffolds will be covered.
BIOE457
Biomedical Electronics & Instrumentation
Credits:
4
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120, BIOE121, BIOE241, PHYS261, MATH246, and PHYS260.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Students learn fundamental concepts of electronics, assembly of electronic components into functional circuits, and integration of functional electronic devices and circuits into a system. In the lab component, students will learn to assemble and evaluate circuits and systems.
BIOE461
Synthetic Biology and Biological Engineering
Credits:
3
Grad Meth:
Reg, P-F
Prerequisite: BIOE120, BIOE121, BIOE241, and MATH246; or permission of ENGR-Fischell Department of Bioengineering department.
Recommended: Completion of BSCI222 and/or BSCI330 recommended.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Students are introduce to the scientific foundation and concepts of synthetic biology and biological engineering. Current examples that apply synthetic biology to fundamental and practical challenges will be emphasized. The course will also address the societal issues of synthetic biology, and briefly examine interests to regulate research in this area.
BIOE462
Therapeutic Development and Delivery
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120, BIOE121, BIOE241, MATH246, and BSCI330; and must have completed or be concurrently enrolled in BIOE340.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE489P or BIOE462.
Formerly: BIOE489P.
The ultimate purpose of the pharmaceutical and biotechnology industries is the development and delivery of therapeutics. This course covers fundamentals of engineering and the pharmaceutical sciences related to therapeutics, including basic pharmaceutics/drug delivery, pharmacokinetics, biomolecular kinetics, and regulatory issues. Specific focus is placed on biotherapeutics, including antibodies and protein engineering,RNA and DNA therapeutics (gene therapy and RNAi), extracellular vesicle biotechnology (exosomes), and cell-based therapies, including stem cells. The use of delivery technologies to enable therapeutics (e.g. nanomedicine) will also be discussed.
BIOE486
Capstone Design II
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: Must have completed BIOE485 in the immediately preceding semester.
Restriction: Senior standing; and must be in Engineering: Bioengineering program; and permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE486 or ENBE486.
Formerly: ENBE486.
This is the second part of the senior capstone design course. This part is independent instruction where faculty mentoring each project team works with students to order supplies, fabricate their proposed design under BIOE485, test the design, write the report and present it to their fellow seniors and board of faculty mentors. Students are taught to convert the blue print of a design to actual device and test it.
BIOE488A
Research Methods in Bioengineering; Molecular Biology
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120, BIOE121, and BSCI330. Restriction: Permission of department.
This course prepares students for a broad range of opportunities by delivering a practical, hands-on laboratory experience that mirrors the real world of research. Students will independently investigate a novel topic related to biomedicine; learn the science and theory behind commonresearch methods; and apply those fundamental techniques, protocols, assays, and technologies to their own experiments. Some of the techniques utilized in the course include: microbiology, protein quantification assays, molecular cloning, PCR, DNA sequencing, novel drug discovery andscreening. This course is designed to prove the same valuable experienceand guidance you would receive in a research lab.
This course prepares students for a broad range of opportunities by delivering a practical, hands-on laboratory experience that mirrors the real world of research. Students will independently investigate a novel topic related to biomedicine; learn the science and theory behind commonresearch methods; and apply those fundamental techniques, protocols, assays, and technologies to their own experiments. Some of the techniques utilized in the course include: microbiology, protein quantification assays, molecular cloning, PCR, DNA sequencing, novel drug discovery andscreening. This course is designed to prove the same valuable experienceand guidance you would receive in a research lab.
BIOE489F
Special Topics in Bioengineering; CFD/FEA Applications in Bioengineering
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisites: BIOE120, BIOE121, MATH241, BIOE241; recommended: BIOE489C.Covers Computational Fluid Dynamics (CFD) and Finite Element Analysis (FEA) as applicable to Bioengineering.
BIOE489H
Special Topics in Bioengineering; BIOE Honors Seminar
Credits:
1 - 3
Grad Meth:
Reg, P-F, Aud
BIOE489M
Special Topics in Bioengineering; Bioprinting in Regenerative Medicine
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE340.
Covers the fundamentals of tissue engineering and regenerative medicine, with an emphasis on the role of biomaterials and stem cells. With this foundation, the course will then consider fundamentals of bioprinting, and how bioprinted constructs may be used in regenerative medicine applications.
Covers the fundamentals of tissue engineering and regenerative medicine, with an emphasis on the role of biomaterials and stem cells. With this foundation, the course will then consider fundamentals of bioprinting, and how bioprinted constructs may be used in regenerative medicine applications.
BIOE489R
Special Topics in Bioengineering; Protein Engineering
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120 and BIOE232. Credit only granted for: CHBE497, BIOE489R, or ENCH648P.
BIOE489T
Special Topics in Bioengineering; Biopharmaceutical Process Development and Manufacturing
Credits:
3
Grad Meth:
Reg, P-F, Aud
Prerequisite: BIOE120. Credit only granted for: BIOE489T or CHBE474
BIOE606
BIOE Graduate Studies II
Credits:
1
Grad Meth:
Reg, Aud
Restriction: Must be in ENGR: PhD Only-Bioengineering (Doctoral) program.
Second semester continued acclimation to the bioengineering graduate program. Students gain exposure to departmental research through lab rotation and to current research in the field through seminar.
BIOE608
Bioengineering Seminar Series
Credits:
1
Grad Meth:
S-F, Aud
Restriction: Must be in one of the following programs (ENGR: PhD Only-Bioengineering (Master's); ENGR: PhD Only-Bioengineering (Doctoral)).
BIOE632
Biophotonic Imaging and Microscopy
Credits:
3
Grad Meth:
Reg, Aud, S-F
Recommended: BIOE420.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Credit only granted for: BIOE432, BIOE632, or BIOE689C.
Principles and instrumentation of various biomedical optical techniques, including fluorescene and Raman spectroscopy, confocal and multi-photon microscopy, optical coherence tomography, and diffuse optical tomography. Biomedical aplications will also be discussed.
BIOE654
Physiology for Bioengineers
Credits:
3
Grad Meth:
Reg, Aud
Restriction: Restricted to Master's of Engineering - Bioengineering students; or permission of Fischell Department of Bioengineering.
Credit only granted for: BIOE654 or BIOE658P.
Formerly: BIOE658P.
Bioengineering-based designs of biomaterials, biomedical devices, imaging and drug delivery agents, tissue engineering, and prosthesis (among others), offer the opportunity to improve health care. This course is aimed at providing biological knowledge to lead bioengineering designs on the basis of biocompatibility and to provide tools to assess their patho-physiological impact in biological systems.
BIOE658B
Special Topics in Bioengineering (M.Eng.); Introduction to Medical Image Analysis
Credits:
3
Grad Meth:
Reg
Restriction: For Master of Engineering students only or with permission of department.
Introduces fundamental topics of medical image analysis, including image enhancement, filtering, feature extraction, segmentation, registration, classification. Topics will be discussed in the context of both traditioanl and deep learning approaches. The course also covers performance metrics and evaluation techniques used by experts in the image analysis communitAlong with digital image processing, this course will review medical imaging modalities, their mechanisms of action, and best practices for modality specific image file types and formats. Students introduced to these topics will learn industry-relevant software and practice digital image processing in MATLAB and Python based environments.
Introduces fundamental topics of medical image analysis, including image enhancement, filtering, feature extraction, segmentation, registration, classification. Topics will be discussed in the context of both traditioanl and deep learning approaches. The course also covers performance metrics and evaluation techniques used by experts in the image analysis communitAlong with digital image processing, this course will review medical imaging modalities, their mechanisms of action, and best practices for modality specific image file types and formats. Students introduced to these topics will learn industry-relevant software and practice digital image processing in MATLAB and Python based environments.
BIOE658E
Special Topics in Bioengineering (M.Eng.); Biomedical Device Development
Credits:
3
Grad Meth:
Reg, Aud
For Master of Engineering students only or with permission of department. Credit only granted for BIOE658E or BIOE689W.
BIOE689
Special Topics in Bioengineering
Credits:
1 - 3
Grad Meth:
Reg
BIOE689M
Special Topics in Bioengineering; Bioprinting in Regenerative Medicine
Credits:
3
Grad Meth:
Reg
Covers the fundamentals of tissue engineering and regenerative medicine, with an emphasis on the role of biomaterials and stem cells. With this foundation, the course will then consider fundamentals of bioprinting, and how bioprinted constructs may be used in regenerative medicine applications.
BIOE689T
Special Topics in Bioengineering; Advanced Biomaterials
Credits:
3
Grad Meth:
Reg, S-F
Restriction: Permission of the Fischell Department of Bioengineering
Advanced biomaterials property (viscoelasticity) and its impact on biomedical systems; interactions of proteins and cells (particularly immune and stem cells) with micro, nano, and macroscale biomaterials; and advanced applications of biomaterials for tissue engineering, regenerative medicine, stem cell therapy, drug delivery, and cancer theranostics.
Advanced biomaterials property (viscoelasticity) and its impact on biomedical systems; interactions of proteins and cells (particularly immune and stem cells) with micro, nano, and macroscale biomaterials; and advanced applications of biomaterials for tissue engineering, regenerative medicine, stem cell therapy, drug delivery, and cancer theranostics.
BIOE689X
Special Topics in Bioengineering; Macroscale Biomechanics
Credits:
3
Grad Meth:
Reg
Topics covered include muscle mechanics, joint mechanics, EMG and EEG signal applications, ultrasonography and elastography, anthropometry, human movement 3-D kinematics, inverse dynamics, forward dynamics, work, power and energy. Biomechanics tools will be used to investigate clinical problems.
BIOE799
Master's Thesis Research
Credits:
1 - 6
Grad Meth:
S-F
BIOE898
Pre-Candidacy Research
Credits:
1 - 8
Grad Meth:
Reg
BIOE899
Doctoral Dissertation Research
Credits:
6
Grad Meth:
S-F
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