Prerequisite: BIOE241, BIOE120, BIOE121, MATH246, and BIOE340.
Restriction: Permission of ENGR-Fischell Department of Bioengineering department.
Jointly offered with: BIOE613.
Credit only granted for: BIOE413, BIOE689J or BIOE613.
Provides an introduction to the role of stem cells in tissue growth and development, the engineering of stem cells and their environments for regenerative medicine applications, and disease modeling. Topics covered will include basic stem cell biology and mechanobiology; experimental methods for growing, differentiating, studying, and characterizing stem cells; stem cell integration into engineered microenvironments (e.g., tissue scaffolds and biomaterials, organ-on-chip devices, 3D-printed biomaterials); stem cell engineering in clinical applications and disease models; and ethical, commercialization, and regulatory issues in the field of stem cell engineering.