Using an interdisciplinary approach to study mental health, mental wellness, and substance use, we will answer questions such as: How has our understanding and treatment of mental health changed throughout history? What are the current prevalence patterns and risk factors associated with mental health conditions? What is the prevention to postvention continuum? What is the role of relationships, families, and communities in addressing mental health? How do we diagnose and treat various mental health disorders using the best available research? And, what are the various mental health disciplines and how do they differ? This course is designed to examine mental health issues across the life course. We will explore the influence of social contexts, including racism and additional forms of othering, on mental health and wellness, and introduce the health systems that support mental health prevention and treatment.