The Integrated Life Sciences (ILS) Honors Program includes a rigorous academic curriculum, a research requirement, a living-learning component, and a service-learning experience. Service has been a tradition since 2012 and was initiated by our students, who wanted service incorporated as part of the ILS mission and values. Our students have contributed more than 6,000 hours of their time and talent to campus and local organizations, and this experiential learning has provided an opportunity to apply classroom studies to the real world. In general, these service experiences are directly relevant to their future careers as life scientists, because they contribute to improved access for all people to quality health care, to engaging STEM education, and/or to sustainable environments. The service-learning experience is introduced in the fall semester of the first year of ILS in HLSC100, and completed with a 1-credit course in the spring.