Covers the fundamentals of protein engineering and its applications in medicine, chemical processes, and energy. Topics will include the structure and function of biological molecules, rational design and directed evolution, construction of protein and peptide libraries, protein screening platforms, methods for characterizing structure and function of biological molecules. Scientific literature will be used to highlight key discoveries and current work in protein engineering.

Analysis and microscopic modeling of systems away from thermal equilibrium. Linear response theory, ergodicity, Brownian motion, Monte Carlo modeling, thermal ratchets, far-from-equilibrium fluctuation relations. Introduction to the theoretical tools of nonequilibrium phenomena and their application to problems in physics, chemistry and biology.

Establishes quantitative principles of how living systems work across scales from cells to organisms to populations while connecting mechanisms, models, and measurements. Traditional lectures are combined with computational modules available in Python, R, and MATLAB to help interdisciplinary students from physics, engineering, mathematics, computing, and the life sciences move from learning in the classroom to doing research in practice.