Recent advances in genomic science and biomedical technologies have increased our understanding of the genetic basis of disease and the interplay between genetics and environmental and behavioral factors. This course will provide a solid background in basic genetics and genomic science and highlight the role of public health professionals in translating breakthroughs in this rapidly transforming field into the clinical setting, program planning, and policy. Topics covered will include the molecular basis for genetic variation, fetal and newborn screening, genetic risk factors for cancer, pharmacogenetics, the role of pathogen genomics in outbreak investigation, and applications of genetic engineering in solving public health issues.