How can we effectively and responsibly partner with artificial intelligences to tackle previously unthinkable problems--and reimagine what's possible for our future? In this course we will explore what it means to think, create, and collaborate in a world where artificial intelligences are not just tools, but teammates. As AIs become increasingly capable partners in thinking, designing, and decision-making, new futures become imaginable--and attainable. We'll examine key cognitive processes such as reasoning, memory, perception, and creativity in both humans and machines. Students will gain hands-on experience working with generative AI tools and autonomous agents on real-world challenges. Along the way, we'll critically assess the risks, ethics, and design choices involved in these hybrid systems--and imagine how human-AI partnerships might shape the future of knowledge, innovation, and society.